PVC coated wire-type membrane selective electrode of procaine and application of.doc

 PAGE \* MERGEFORMAT 5 PVC coated wire-type membrane selective electrode of procaine and application of Author: Yue Li Donghui, Wang Lian-Shan Chen Jing-stand fall [Abstract] reported a kind of order to procaine association complex with the iodine molecule compounds for the electrical activity of new solid-state PVC membrane selective electrode of procaine coated wire electrode linear response range of 1.0 * 10-1 ~ 7.9 * 10-5mol / L, differential of 51mV / pC, a detection limit of 5.0 * 10-5mol / L. The electrode has fast response, good reproducibility, using a standard curve of this electrode on the content of procaine hydrochloride injection was determined by this method is simple, the results in line with the pharmacopoeia method. [Keywords:] procaine coated wire ion-selective electrode Procaine hydrochloride injection is a local anesthetic, its low toxicity, no addiction, for infiltration anesthesia, block anesthesia, spinal anesthesia, epidural anesthesia and partial closure of treatment, the general administration of injections. Determination of its content with Chinese Pharmacopoeia method [1], liquid chromatography method [2], spectrophotometry [3], plasma atomic emission spectrometry [4] and ion-selective electrode method [5,6] and so on. In this study, procaine and the iodine formed by electro-active materials for the association complex was prepared by solid-state PVC membrane coated wire-type procaine-selective electrodes, and use of the electrode pairs of the content of procaine injection was the measurement results in line with the pharmacopoeia method. An experimental part of the 1.1 The main instruments and reagents PXJ-IB digital ion meter (Jiangsu Electroanalytical Instrument Factory); 79-type magnetic heating stirrer; procaine hydrochloride (Hebei Hongbao Pharmaceutical Co., Ltd.). In addition to PVC for industrial goods, the rest were analytically pure reagents. 1.2 Preparation of electro-active materials To 0.2mol / L potassi