QIANGGUBAO ovariectomized rat model of osteoporosis the impact of the uterus.docVIP

 PAGE \* MERGEFORMAT 10 QIANGGUBAO ovariectomized rat model of osteoporosis the impact of the uterus [Keywords:] osteoporosis;,, rats;,, uterus;,, intimal Abstract: Objective To observe the compound preparation of QIANGGUBAO (JGB) in the prevention and treatment of osteoporosis in ovariectomized rat uterus during the intima-media thickness and its impact. Methods 32 3-month-old Wistar female rats were randomly divided into four groups, as required surgical castration OK, and then were gavage saline, diethylstilbestrol, QIANGGUBAO 8 weeks later were killed, rat uterus weighing wet weight and do pathology, image digital analysis of endometrial thickness. The results compared with diethylstilbestrol treatment, treatment of rats QIANGGUBAO uterine wet weight / body weight (UW) ratio, and intima-media thickness (EET) has a marked change, the difference was significant. Conclusion QIANGGUBAO ovariectomized rats can maintain normal growth of the endometrium, estrogen replacement therapy to prevent the harm to the uterus. Keywords:: osteoporosis; rats; uterus; endometrium Abstract: ObjectiveTo investigate the effect of JGB on the uterus weight and endometrium epithelial thickness in the OVX osteoprosis rats.Methods32 Wistar female rats were randomly divided into 4 groups: the normal, model, JGB treated and diethylstibestrol treated.The normal group was only shamly operated and other three groups were ovariectomized and all were fed with medicine for two months and then killed.The rats uteruses were taken out to weight and to be processed into 5micron, hematoxylin and esosin stained sections, then used to determine the endometrium epithelial thickness. ResultsCompared with the diethylstibestrol treated group, the JGB treated group decreased EET and UW significantiy.ConclusionJGB can sustain the normal function in the rats uterus and avoid the sidereaction in the therapy of diethylstibestrol. Keywords:: Osteoprosis; Rats; Uterine; Ednometrium epithelial Senile os