Risk factors of lacunar infarction Study.doc

 PAGE \* MERGEFORMAT 12 Risk factors of lacunar infarction Study [Abstract] Objective To investigate the lacunar infarction (LI) disease-related risk factors. Method of forward-looking registration in July 2005 ~ September 2006 of 136 cases of consecutive hospitalized patients with ischemic stroke, according to cranial CT or MRI scans were divided into two groups and non-cavity Terrier LI group (NLI group), single cavity Terrier Group (SLI group), multiple-cavity Terrier Group (MLI group), the introduction of single factor logistic regression and multivariate analysis. Results (1) LI / NLI group hypertension, diabetes, smoking, physical activity, cholesterol, high density lipoprotein (HDL  C), low density lipoprotein (LDL  C), fibrinogen, there are differences; multi - logistic regression showed LI of the major risk factor for hypertension and high-density lipoprotein. (2) SLI / MLI group family history of hypertension, white matter degeneration, fasting blood glucose, cholesterol, triglycerides, LDL  C, HDL  C and fibrinogen there are differences. Conclusions (1) LI incidence is the result of multiple factors, multiple logistic regression analysis showed that LI is the major factor in the pathogenesis of high blood pressure and HDL  C, high blood pressure are risk factors, HDL  C is a protective factor. (2) SLI and MLI in the incidence of risk factors are different, there is family history of hypertension and cerebral white matter degeneration susceptible to MLI, fasting blood glucose, cholesterol, triglycerides, LDL  C, high fibrinogen, HDL  C Low are susceptible to MLI. [Keywords:] lacunar infarction risk factors for hypertension Lacunar infarction (lacunar infarction, LI) is a Chinese common type of ischemic stroke, cerebrovascular diseases in China accounted for 19%. LI in the pathogenesis of the more controversial: Fisher’s research suggests that long-term high blood pressure caused by small artery disease is the leading cause of LI, wh