The emergence of antimicrobial resistance and countermeasures against drug-resistant microorganisms.docVIP

 PAGE \* MERGEFORMAT 20 The emergence of antimicrobial resistance and countermeasures against drug-resistant microorganisms [Abstract] Objective rational use of antimicrobial drugs, reduce the development of drug resistance, blocking the spread of drug-resistant infections. Method from the generation and spread of drug resistance study and formulation of the laws against drug-resistant approaches. The results of drug resistance, the hospital is an important part, the hospital should be to contain and control multi-drug-resistant microorganisms high proportion of the microbiology laboratory to establish a good, not to prevent infection while the use of antimicrobial drugs, strengthen the PK / PD studies, to close or downsize MSW. Conclusion antimicrobial drug resistance is a natural biological phenomenon, bacteria and other microorganisms by the selective pressure of antimicrobial drug use responses. Therefore, the containment of drug resistance occurred in a fundamental way is to reduce unnecessary antimicrobial drugs, inappropriate or unreasonable use. [Keywords:] antibacterial agents; drug resistance; antimicrobial PK / PD Drug resistance (resistance) is the micro-organisms to antimicrobial drugs, compared confrontational, is the process of microbial evolution laws of nature, but also a long-term evolution of microbial resistance gene in the inevitable result. Because antibiotics kill the sensitive bacteria, while the survival and reproduction of resistant invalid, so resistance is the overuse and misuse of antimicrobials is an inevitable consequence of drugs. At present, the emergence and spread of resistant bacteria has become a worldwide problem. Such as pneumonia, tuberculosis and malaria, because of its micro-organisms for many of the resistance to existing drugs are becoming more difficult to treat. Resistance is how the formation and development? How to curb this threat? Has become a hot issue of global concern. A type of drug resistance