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The zipper mechanism in phagocytosis energetic requirements and variability in phagocytic cup shape 英文论文文献
Tollisetal.BMCSystemsBiology2010,4:149
/1752-0509/4/149
RESEARCH ARTICLE
OpenAccess
Thezippermechanisminphagocytosis:energetic
requirementsandvariabilityinphagocytic
cupshape
SylvainTollis1,2,AnnaEDart2,3,GeorgeTzircotis2,3,RobertGEndres1,2*
Abstract
Background:Phagocytosisisthefundamentalcellularprocessbywhicheukaryoticcellsbindandengulfparticles
bytheircellmembrane.Particleengulfmentinvolvesparticlerecognitionbycell-surfacereceptors,signalingand
remodelingoftheactincytoskeletontoguidethemembranearoundtheparticleinazipper-likefashion.Despite
thesignalingcomplexity,phagocytosisalsodependsst
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