Top scoring pairs for feature selection in machine learning and applications to cancer outcome prediction 英文论文文献.docVIP

Shietal.BMCBioinformatics2011,12:375 /1471-2105/12/375 RESEARCH ARTICLE OpenAccess Topscoringpairsforfeatureselectioninmachine learningandapplicationstocanceroutcome prediction PingShi1,2*,SurajitRay2,QifuZhu3andMarkAKon2 Abstract Background:Thewidelyusedktopscoringpair(k-TSP)algorithmisasimpleyetpowerfulparameter-free classifier.Itowesitssuccessinmanycancermicroarraydatasetstoaneffectivefeatureselectionalgorithmthatis basedonrelativeexpressionorderingofgenepairs.However,itsgeneralrobustnessdoesnotextendtosome difficultdatasets,suchasthoseinvolvingcanceroutcomeprediction,whichmaybeduetother