Translating tumor biology into personalized treatment planning analytical performance characteristics of the Oncotype DX? Colon Cancer Assay 英文论文文献.docVIP
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Translating tumor biology into personalized treatment planning analytical performance characteristics of the Oncotype DX? Colon Cancer Assay 英文论文文献
Clark-Langoneetal.BMCCancer2010,10:691
/1471-2407/10/691
TECHNICAL ADVANCE
OpenAccess
Translatingtumorbiologyintopersonalized
treatmentplanning:analyticalperformance
characteristicsoftheOncotypeDX?ColonCancer
Assay
KimMClark-Langone1*,ChithraSangli2,JayadeviKrishnakumar1,DrewWatson1
Abstract
Background:TheOncotypeDX?ColonCancerAssayisanewdiagnostictestfordeterminingthelikelihoodof
recurrenceinstageIIcoloncancerpatientsaftersurgicalresectionusingfixedparaffinembedded(FPE)primary
colontumortissue.LiketheOncotypeDXBreastCancerAssay,thisisahighcomplexity,multi-analyte,reverse
transcription(RT)p
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