Tumor suppressor BLU inhibits proliferation of nasopharyngeal carcinoma cells by regulation of cell cycle, c-Jun N-terminal kinase and the cyclin D1 promoter 英文论文文献.docVIP
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Tumor suppressor BLU inhibits proliferation of nasopharyngeal carcinoma cells by regulation of cell cycle, c-Jun N-terminal kinase and the cyclin D1 promoter 英文论文文献
Zhangetal.BMCCancer2012,12:267
/1471-2407/12/267
RESEARCH ARTICLE
OpenAccess
TumorsuppressorBLUinhibitsproliferationof
nasopharyngealcarcinomacellsbyregulationof
cellcycle,c-JunN-terminalkinaseandthecyclin
D1promoter
XiangningZhang1,2*,HuiLiu1,2,BinbinLi1,2,PeichunHuang1,2,JianyongShao3andZhiweiHe1,2*
Abstract
Background:Tumorsuppressorgenesfunctiontoregulateandblocktumorcellproliferation.Toexplorethe
mechanismsunderlyingthetumorsuppressionofBLU/ZMYND10geneonafrequentlylosthumanchromosomal
region,anadenoviralvectorwithBLUcDNAinsertwasconstructed.
Methods:BLUwasre-expressedinnasopharyngealca
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