Tumor suppressor genes are frequently methylated in lymph node metastases of breast cancers 英文论文文献.docVIP
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Tumor suppressor genes are frequently methylated in lymph node metastases of breast cancers 英文论文文献
Fengetal.BMCCancer2010,10:378
/1471-2407/10/378
RESEARCH ARTICLE
OpenAccess
Tumorsuppressorgenesarefrequently
methylatedinlymphnodemetastasesofbreast
cancers
WeiweiFeng1?,RosariaOrlandi2?,NaiqingZhao3,MariaLuisaCarcangiu2,EldaTagliabue2,JiaXu4,
RobertCBastJr4,YinhuaYu1,4*
Abstract
Introduction:Metastasisrepresentsamajoradversestepintheprogressionofbreastcarcinoma.Lymphnode
invasionisthemostrelevantprognosticfactor;howeverlittleisknownonthemoleculareventsassociatedwith
lymphnodemetastasisprocess.Thisstudyistoinvestigatethestatusandroleofmethylationinlymphnode
metastatictumors.
Materialsandmeth
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