Tumour-specific HMG-CoAR is an independent predictor of recurrence free survival in epithelial ovarian cancer 英文论文文献.docVIP
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Tumour-specific HMG-CoAR is an independent predictor of recurrence free survival in epithelial ovarian cancer 英文论文文献
Brennanetal.BMCCancer2010,10:125
/1471-2407/10/125
RESEARCH ARTICLE
OpenAccess
Tumour-specificHMG-CoARisanindependent
predictorofrecurrencefreesurvivalinepithelial
ovariancancer
DonalJBrennan1,2*,JennyBr?ndstedt3,EltonRexhepaj2,MichaelFoley4,FredrikPontén5,MathiasUhlén6,
WilliamMGallagher2,DarranPO’Connor2,ColmO’Herlihy4,KarinJirstrom3,7
Abstract
Background:Ourgrouppreviouslyreportedthattumour-specificexpressionoftherate-limitingenzymeinthe
mevalonatepathway,3-hydroxy-3-methylglutharyl-coenzymeAreductase(HMG-CoAR)isassociatedwithmore
favourabletumourparametersandagoodprognosisinbreastcancer
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