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Up-regulation of METCAMMUC18 promotes motility, invasion, and tumorigenesis of human breast cancer cells 英文论文文献.docVIP

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Up-regulation of METCAMMUC18 promotes motility, invasion, and tumorigenesis of human breast cancer cells 英文论文文献.doc

    Up-regulation of METCAMMUC18 promotes motility, invasion, and tumorigenesis of human breast cancer cells 英文论文文献

    Zengetal.BMCCancer2011,11:113 /1471-2407/11/113 RESEARCH ARTICLE OpenAccess Up-regulationofMETCAM/MUC18promotes motility,invasion,andtumorigenesisofhuman breastcancercells Guo-fangZeng1,2,Shao-xiCai1*andGuang-JerWu2* Abstract Background:ConflictingresearchhasidentifiedMETCAM/MUC18,anintegralmembranecelladhesionmolecule (CAM)intheIg-likegenesuper-family,asbothatumorpromoterandatumorsuppressorinthedevelopmentof breastcancer.Toresolvethis,wehavere-investigatedtheroleofthisCAMintheprogressionofhumanbreast cancercells. Methods:Threebreastcancercelllineswereusedforthetests:oneluminal-likebreastca

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