Validated stability-indicating spectrofluorimetric methods for the determination of ebastine in pharmaceutical preparations 英文论文文献.docVIP

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Validated stability-indicating spectrofluorimetric methods for the determination of ebastine in pharmaceutical preparations 英文论文文献.doc

Validated stability-indicating spectrofluorimetric methods for the determination of ebastine in pharmaceutical preparations 英文论文文献

Ibrahimetal.ChemistryCentralJournal2011,5:11 /content/5/1/11 RESEARCH ARTICLE OpenAccess Validatedstability-indicatingspectrofluorimetric methodsforthedeterminationofebastinein pharmaceuticalpreparations FawziaIbrahim,MohieKhaledSharafEl-Din,ManalIbrahimEid,MaryEliasKamelWahba* Abstract Twosensitive,selective,economic,andvalidatedspectrofluorimetricmethodsweredevelopedforthe determinationofebastine(EBS)inpharmaceuticalpreparationsdependingonreactionwithitstertiaryamino group.MethodIinvolvescondensationofthedrugwithmixedanhydrides(citricandaceticanhydrides)producing aproductwithintensefluore

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