Validation of cytoplasmic-to-nuclear ratio of survivin as an indicator of improved prognosis in breast cancer 英文论文文献.docVIP
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Validation of cytoplasmic-to-nuclear ratio of survivin as an indicator of improved prognosis in breast cancer 英文论文文献
Rexhepajetal.BMCCancer2010,10:639
/1471-2407/10/639
RESEARCH ARTICLE
OpenAccess
Validationofcytoplasmic-to-nuclearratioof
survivinasanindicatorofimprovedprognosis
inbreastcancer
EltonRexhepaj1,KarinJirstrom2,DarranPO’Connor1,SallyannLO’Brien1,GoranLandberg2,MichaelJDuffy3,4,
DonalJBrennan1,WilliamMGallagher1*
Abstract
Background:Conflictingdataexistregardingtheprognosticandpredictiveimpactofsurvivin(BIRC5)inbreast
cancer.Wepreviouslyreportedsurvivincytoplasmic-to-nuclearratio(CNR)asanindependentprognosticindicator
inbreastcancer.Here,wevalidatesurvivinCNRinaseparateandextendedcohort.Further
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