Variants of the Matrix Metalloproteinase-2 but not the Matrix Metalloproteinase-9 genes significantly influence functional outcome after stroke 英文论文文献.docVIP

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Variants of the Matrix Metalloproteinase-2 but not the Matrix Metalloproteinase-9 genes significantly influence functional outcome after stroke 英文论文文献.doc

Variants of the Matrix Metalloproteinase-2 but not the Matrix Metalloproteinase-9 genes significantly influence functional outcome after stroke 英文论文文献

Mansoetal.BMCMedicalGenetics2010,11:40 /1471-2350/11/40 RESEARCH ARTICLE OpenAccess VariantsoftheMatrixMetalloproteinase-2butnot theMatrixMetalloproteinase-9genessignificantly influencefunctionaloutcomeafterstroke HelenaManso1,2,3,TiagoKrug1,4,Jo?oSobral1,2,3,IsabelAlbergaria2,GiselaGaspar2,JoséMFerro5, SofiaAOliveira1,4,AstridMVicente1,2,3* Abstract Background:Multiplelinesofevidencesuggestthatgeneticfactorscontributetostrokerecovery.Thematrix metalloproteinases-2(MMP-2)and-9(MMP-9)aremodulatorsofextracellularmatrixcomponents,withimportant regulatoryfunctionsintheCentralNervousSystem(CNS).

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