Variants of the Matrix Metalloproteinase-2 but not the Matrix Metalloproteinase-9 genes significantly influence functional outcome after stroke 英文论文文献.docVIP
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Variants of the Matrix Metalloproteinase-2 but not the Matrix Metalloproteinase-9 genes significantly influence functional outcome after stroke 英文论文文献
Mansoetal.BMCMedicalGenetics2010,11:40
/1471-2350/11/40
RESEARCH ARTICLE
OpenAccess
VariantsoftheMatrixMetalloproteinase-2butnot
theMatrixMetalloproteinase-9genessignificantly
influencefunctionaloutcomeafterstroke
HelenaManso1,2,3,TiagoKrug1,4,Jo?oSobral1,2,3,IsabelAlbergaria2,GiselaGaspar2,JoséMFerro5,
SofiaAOliveira1,4,AstridMVicente1,2,3*
Abstract
Background:Multiplelinesofevidencesuggestthatgeneticfactorscontributetostrokerecovery.Thematrix
metalloproteinases-2(MMP-2)and-9(MMP-9)aremodulatorsofextracellularmatrixcomponents,withimportant
regulatoryfunctionsintheCentralNervousSystem(CNS).
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