Viral-mediated oncolysis is the most critical factor in the late-phase of the tumor regression process upon vaccinia virus infection 英文论文文献.docVIP

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Viral-mediated oncolysis is the most critical factor in the late-phase of the tumor regression process upon vaccinia virus infection 英文论文文献.doc

Viral-mediated oncolysis is the most critical factor in the late-phase of the tumor regression process upon vaccinia virus infection 英文论文文献

Weibeletal.BMCCancer2011,11:68 /1471-2407/11/68 RESEARCH ARTICLE OpenAccess Viral-mediatedoncolysisisthemostcriticalfactor inthelate-phaseofthetumorregressionprocess uponvacciniavirusinfection StephanieWeibel1,2,3?,ViktoriaRaab1,2,3?,YongAYu4,AndreaWorschech1,2,3,4,5,EnaWang5, FrancescoMMarincola5,AladarASzalay1,2,3,4* Abstract Background:Inprinciple,theeliminationofmalignanciesbyoncolyticvirotherapycouldproceedbydifferent mechanisms-e.g.tumorcellspecificoncolysis,destructionofthetumorvasculatureorananti-tumoral immunologicalresponse.Inthisstudy,weanalyzedthecontributionofthesefactorstoeluc

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