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Visualizing Meta-Features in Proteomic Maps 英文论文文献
Giannopoulouetal.BMCBioinformatics2011,12:308
/1471-2105/12/308
RESEARCH ARTICLE
OpenAccess
VisualizingMeta-FeaturesinProteomicMaps
EugeniaGGiannopoulou1,2*,GeorgeLepouras2andEliasSManolakos3*
Abstract
Background:Thestepsofahigh-throughputproteomicsexperimentincludetheseparation,differentialexpression
andmassspectrometry-basedidentificationofproteins.However,thelastandmorechallengingstepisinferring
thebiologicalroleoftheidentifiedproteinsthroughtheirassociationwithinteractionnetworks,biological
pathways,analysisoftheeffectofpost-translationalmodifications,andotherprotein-relatedinformation.
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