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Vitamin D3 receptor is highly expressed in Hodgkin’s lymphoma 英文论文文献
Rennéetal.BMCCancer2012,12:215
/1471-2407/12/215
RESEARCH ARTICLE
OpenAccess
VitaminD3receptorishighlyexpressedin
Hodgkin’ slymphoma
ChristophRenné1*,AlexanderHBenz1,2andMartinLHansmann1
Abstract
Background:Hodgkinlymphoma(HL)isoneofthemostfrequentlymphomainthewesternworld.Despiteagood
overallprognosis,somepatientssufferrelapsingtumorswhicharedifficulttocure.OveralongperiodVitaminDhas
beenshowntobeapotentialtreatmentforcancer.VitaminDactsviathevitaminDreceptor,anuclearreceptor,
actingasaninducibletranscriptionfactor.WeaimedtoinvestigatetheexpressionofvitaminDreceptorasapossible
diagnosticma
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