Ways and means of coping with uncertainties of the relationship of the genetic blue print to protein structure and function in the cell 英文论文文献.docVIP

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Ways and means of coping with uncertainties of the relationship of the genetic blue print to protein structure and function in the cell 英文论文文献.doc

Ways and means of coping with uncertainties of the relationship of the genetic blue print to protein structure and function in the cell 英文论文文献

HelmreichCellCommunicationandSignaling2010,8:26 /content/8/1/26 COMMENTARY OpenAccess Waysandmeansofcopingwithuncertaintiesof therelationshipofthegeneticblueprintto proteinstructureandfunctioninthecell ErnstJMHelmreich Abstract Asoneofthedisciplinesofsystemsbiology,proteomicsiscentraltoenablingtheelucidationofproteinfunction withinthecell;furthermore,thequestionofhowtodeduceproteinstructureandfunctionfromthegeneticread- outhasgainednewsignificance.Thisproblemisofparticularrelevanceforproteinsengagedincellsignalling.In dealingwiththisquestion,Ishallcriticallycommentonthereliabilityandpredicta

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