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Which clustering algorithm is better for predicting protein complexes 英文论文文献
Moschopoulosetal.BMCResearchNotes2011,4:549
/1756-0500/4/549
RESEARCH ARTICLE
OpenAccess
Whichclusteringalgorithmisbetterfor
predictingproteincomplexes?
CharalamposNMoschopoulos1,2*,GeorgiosAPavlopoulos3,4*,ErnestoIacucci4*,JanAerts4*,
SpiridonLikothanassis2*,ReinhardSchneider5,6 andSophiaKossida1*
Abstract
Background:Protein-Proteininteractions(PPI)playakeyroleindeterminingtheoutcomeofmostcellular
processes.Thecorrectidentificationandcharacterizationofproteininteractionsandthenetworks,whichthey
comprise,iscriticalforunderstandingthemolecularmechanismswithinthecell.Large-scaletechniquessuc
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