Whole-genome amplified DNA from stored dried blood spots is reliable in high resolution melting curve and sequencing analysis 英文论文文献.docVIP

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Whole-genome amplified DNA from stored dried blood spots is reliable in high resolution melting curve and sequencing analysis 英文论文文献.doc

Whole-genome amplified DNA from stored dried blood spots is reliable in high resolution melting curve and sequencing analysis 英文论文文献

Winkeletal.BMCMedicalGenetics2011,12:22 /1471-2350/12/22 TECHNICAL ADVANCE OpenAccess Whole-genomeamplifiedDNAfromstoreddried bloodspotsisreliableinhighresolutionmelting curveandsequencinganalysis BoGWinkel1*,MadsVHollegaard2,MortenSOlesen1,JesperHSvendsen1,3,StigHauns?1,3,DavidMHougaard2, JacobTfelt-Hansen1 Abstract Background:Theuseofdriedbloodspots(DBS)samplesingenomicworkuphasbeenlimitedbytherelativelow amountsofgenomicDNA(gDNA)theycontain.ItremainstobeproventhatwholegenomeamplifiedDNA (wgaDNA)fromstoredDBSsamples,constitutesareliablealternativetogDNA. Wewantedtocomparemeltingcurvesands

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