Why do results conflict regarding the prognostic value of the methylation status in colon cancers the role of the preservation method 英文论文文献.docVIP

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Why do results conflict regarding the prognostic value of the methylation status in colon cancers the role of the preservation method 英文论文文献.doc

Why do results conflict regarding the prognostic value of the methylation status in colon cancers the role of the preservation method 英文论文文献

Tournieretal.BMCCancer2012,12:12 /1471-2407/12/12 RESEARCH ARTICLE OpenAccess Whydoresultsconflictregardingtheprognostic valueofthemethylationstatusincoloncancers? theroleofthepreservationmethod BenjaminTournier1,2*,CarolineChapusot1,2,3,EmilieCourcet1,2,LaurentMartin2,4,C?meLepage1,3,JeanFaivre1,3 andFran?oisePiard1,2,3,4 Abstract Background:Incolorectalcarcinoma,extensivegenepromoterhypermethylationiscalledtheCpGisland methylatorphenotype(CIMP).ExplainingwhystudiesonCIMPandsurvivalyieldconflictingresultsisessential. MostexperimentstomeasureDNAmethylationrelyonthesodiumbisulfiteconversiono

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Why do results conflict regarding the prognostic value of the methylation status in colon cancers the role of the preservation method 英文论文文献.docVIP