漆酶氧化醇羟基.pdf

Sournrtl of Mxular Catalysis A: Chemical IOX(1996) 5-9 A new catalytic method for the oxidation of substituted benzyl alcohols LO the corresponding benzaldehydes by molecular oxygen using the enzyme/cofactor system laccase/2,2’-azIno-tis(3-ethyl-benzothiazo~~ne-6-sulfonic acid) is presented. The reaction proceeds under very mild conditions giving the product in quantitative yields. The enzyme requires at least one free w-rho-position in the substrate molecule for the reaction to proceed. Lactase catafyzes the four-electron reduction of molecular oxygen to water an The enzyme Paccase (benzene dizes the substrate. In this process, phenols react Use; EC 1.10.3.1 via W ato ~bstract~o~, i.e., one er molecule in electron, ducing phenoxyl ra ergo a variety of su uent reactions. There- re, the reaction of 1 se with phenols is not important in h -yield syntheses. While reac- been intensively investigated because of its ca- tions of lactase th pjrenols have been corn pability to degrade lignin [8], and it