张新祥《生化分析》20140401-PTM-MS.pptxVIP

MS analysis of pathogen induced post-translational modifications;Outline;3;4;2001;“…..The finding that the human genome contains fewer genes than previously predicted might be compensated for by combinatorial diversity generated at the level of...posttranslational modification of proteins….” J. C. Venter, et al., Science (2001), 291, 1304.;Beyond the Central Dogma;8;9;10;PTMs by pathogens;Legionella Uses AMPylation and Phosphocholination to Regulate the Rab1 GTPase;Pathogens Antagonize Host Signaling;14;15;16;17;18;19;20;21;22;23;24;25;26;Conclusions;作业：;29