RAG1 oligomerization states and secondary structural properties an initial characterization of V(D)J recombinase complex formation 外文参考文献.docVIP

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RAG1 oligomerization states and secondary structural properties an initial characterization of V(D)J recombinase complex formation 外文参考文献.doc

RAG1 oligomerization states and secondary structural properties an initial characterization of V(D)J recombinase complex formation 外文参考文献

Spectroscopy18(2004)311–322 IOSPress 311 RAG1oligomerizationstatesandsecondary structuralproperties:aninitial characterizationofV(D)Jrecombinase complexformation LeAnnJ.GodderzandKarlaK.Rodgers ? DepartmentofBiochemistryandMolecularBiology,UniversityofOklahomaHealthSciencesCenter, 940StantonL.YoungBlvd,OklahomaCity,OK73104,USA Abstract.Therecombinationactivatinggeneproducts(RAG1and2)catalyzetheinitialDNAcleavagestepsduringV(D)J recombination for thediversi?cation of the immune repertoire. Asthe fundamental properties of theRAG proteins remain largelyunknown,ourobjectiveistoinvestigatetheself

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