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Raman study of HIV TAR structural stability 外文参考文献
Spectroscopy22(2008)267–277
DOI10.3233/SPE-2008-0349
IOSPress
267
RamanstudyofHIVTARstructuralstability
JanVachou?ekandJosef?tˇepánek
?
FacultyofMathematicsandPhysics,CharlesUniversity,Prague,CzechRepublic
Abstract.StructuralcharacteristicsofacentralsegmentoftheHIVRNAtrans-activationresponseelement(TAR)havebeen
studiedinaqueoussolution.Theinvestigatedsegment(TAR-14),comprisingnucleotides26–39ofthewild-typeHIVgenome
(GAGC-CUGGGA-GCUCsequence),formstheTARapicalhairpinwithasix-baseloopandastemof4basepairs.Raman
spectra were recorded in a wide temperature range and the spectral series analyzed b
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