Reactive Oxygen Species and Age-Related Genes p66Shc, Sirtuin, FoxO3 and Klotho in Senescence 外文参考文献.docVIP

OpiniOn paper OpiniOn paper Oxidative Medicine and CellularLongevity 3:2, 77-85; March/april 2010; ? 2010 Landes Bioscience Reactive oxygen species and age-related genes p66Shc, sirtuin, FoxO3 and klotho in senescence Igor Afanas’ev Vitamin Research Institute; Moscow, Russia R eactive oxygen species (ROS) super- noted that the programmed mechanisms oxide and hydrogen peroxide per- of senescence and apoptosis might prevent form important signaling functions in the conversion of normal cells into poten- many physiological and pathophysi- tial cancer cells