Regulation of Bile Acid and Cholesterol Metabolism by PPARs 外文参考文献.docVIP

HindawiPublishingCorporation PPARResearch Volume2009,ArticleID501739,15pages doi:10.1155/2009/501739 ReviewArticle RegulationofBileAcidandCholesterolMetabolismbyPPARs TiangangLiandJohnY.L.Chiang DepartmentofIntegrativeMedicalSciences,NortheasternOhioUniversitiesCollegeofMedicine,Rootstown,OH44272,USA CorrespondenceshouldbeaddressedtoJohnY.L.Chiang,jchiang@ Received1April2009;Accepted15May2009 RecommendedbyJamesP.Hardwick Bile acids are amphipathic molecules synthesized from cholesterol in the liver. Bile acid synthesis is a major pathway for hepaticcholesterolcatabolism.Bileacidsynthesisgene