CATH—ahierarchicclassificationofproteindomainstructures.pptVIP

CATH — a hierarchic classification of protein domain structures CA Orengo, AD Michie and JM Thornton Structure, vol.5, pp.1093–1108, 1997 Abstract Protein evolution gives rise to families of structurally related proteins, within which sequence identities can be extremely low. As a result, structure-based classifications can be effective at identifying unanticipated relationships in known structures and in optimal cases function can also be assigned. The ever increasing number of known protein structures is too large to classify all proteins manually, therefore, automatic methods are