Acute Coronary Syndrome in Patients with Prior Coronary Artery Bypass Surgery Observations from a 20-Year Registry in a Middle-Eastern Country 英文参考文献.docVIP

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Acute Coronary Syndrome in Patients with Prior Coronary Artery Bypass Surgery Observations from a 20-Year Registry in a Middle-Eastern Country 英文参考文献.doc

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Acute Coronary Syndrome in Patients with Prior Coronary Artery Bypass Surgery Observations from a 20-Year Registry in a Middle-Eastern Country 英文参考文献

AcuteCoronarySyndromeinPatientswithPrior CoronaryArteryBypassSurgery:Observationsfroma20- YearRegistryinaMiddle-EasternCountry RafidAl-Aqeedi,NidalAsaad,AwadAl-Qahtani,RajvirSingh,HajarA.AlBinali,AbdulWahidAlMulla, JassimAlSuwaidi* DepartmentofCardiologyandCardiovascularSurgery,HeartHospitalHamadMedicalCorporation(HMC),Doha,Qatar Abstract Objectives: Clinical characteristics and trends in the outcome of acute coronary syndrome (ACS) in patients with prior coronaryarterybypassgraftsurgery(CABG)areunclear.Theaimofthisstudywastoevaluateclinicalcharacteristics,in- hospitaltreatment,andoutcomesinpatientspresentedwithACSwithorwithoutahistoryofpriorCABGover2decades. Methods:Datawerederivedfromhospital-basedstudyforcollecteddatafrom1991through2010ofpatientshospitalized withACSinDoha,Qatar.DatawereanalyzedaccordingtotheirhistoryofpriorCABG.Baselineclinicalcharacteristics,in- hospitaltreatment,andoutcomewerecompared. Results:Atotal16,750consecutivepatientswithACSwerestudied,ofwhich693(4.1%)hadpriorCABG.Patientswithprior CABGwereolder(mean60.5611vs.53612years;P=0.001),morelikelytobefemalesandhavemorecardiovascularrisk factorsthanthenon-CABGgroup.PriorCABGpatientshadlargerinfarctsize,werelesslikelytoreceivereperfusiontherapy, early invasive therapy and more likely to receive evidence-based therapies when compared to non-CABG patients. In- hospitalmortalityandstrokerateswerecomparablebetweenthe2groups.Over2decades,therewasreductioninthein- hospitalmortalityratesandstrokeratesinbothgroups(CABG,death;13.2%to4%,stroke;1.9%to0.0%,non-CABG,death; 10%to3.2%,stroke1.0%to0.1%;all,p=0.001). Conclusion:Significantreductionin-hospitalmorbidityandmortalityamongACSpatientswithpriorCABGovera20-year period. Citation:Al-AqeediR,AsaadN,Al-QahtaniA,SinghR,AlBinaliHA,etal.(2012)AcuteCoronarySyndromeinPatientswithPriorCoronaryArteryBypassSurgery: Observationsfroma20-YearRegistryinaMiddle-EasternCountry.PLoSONE7(7):e40571.doi:10.1371/journal.pone.0040571 Editor:ClaudioMoretti,S.G.BattistaHospital,