Lambs with Scrapie Susceptible Genotypes Have Higher Postnatal Survival 英文参考文献.docVIP

LambswithScrapieSusceptibleGenotypesHaveHigher PostnatalSurvival RamiM.Sawalha1*,SusanBrotherstone2,JoanneConington1,BeatrizVillanueva1 1ScottishAgriculturalCollege,Edinburgh,UnitedKingdom,2SchoolofBiologicalSciences,UniversityofEdinburgh,Edinburgh,UnitedKingdom Background. Prion protein (PrP) alleles associated with scrapie susceptibility persist in many sheep populations even with high frequencies despite centuries of selection against them. This suggests that scrapie susceptibility alleles have a pleiotropic effect or are associated with fitness or other traits that have been subject to