Lapatinib, a Dual EGFR and HER2 Tyrosine Kinase Inhibitor, Downregulates Thymidylate Synthase by Inhibiting the Nuclear Translocation of EGFR and HER2 英文参考文献.docVIP

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Lapatinib, a Dual EGFR and HER2 Tyrosine Kinase Inhibitor, Downregulates Thymidylate Synthase by Inhibiting the Nuclear Translocation of EGFR and HER2 英文参考文献.doc

Lapatinib, a Dual EGFR and HER2 Tyrosine Kinase Inhibitor, Downregulates Thymidylate Synthase by Inhibiting the Nuclear Translocation of EGFR and HER2 英文参考文献

Lapatinib,aDualEGFRandHER2TyrosineKinase Inhibitor,DownregulatesThymidylateSynthaseby InhibitingtheNuclearTranslocationofEGFRandHER2 Hwang-PhillKim1,Young-KwangYoon1,Jin-WonKim2,Sae-WonHan2,Hyung-SeokHur1,JinahPark1, Ju-HeeLee1,Do-YounOh1,2,Seock-AhIm1,2,Yung-JueBang1,2,Tae-YouKim1,2 * 1CancerResearchInstitute,SeoulNationalUniversityCollegeofMedicine,Seoul,Korea,2DepartmentofInternalMedicine,SeoulNationalUniversityCollegeofMedicine, Seoul,Korea Abstract Background:Epidermalgrowthfactorreceptortyrosinekinaseinhibitor(EGFR-TKI)hasbeenshowntoexertasynergistic antitumor effect when combined with

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