LDx Estimation of Linkage Disequilibrium from High-Throughput Pooled Resequencing Data 英文参考文献.docVIP

LDx:EstimationofLinkageDisequilibriumfromHigh- ThroughputPooledResequencingData AlisonF.Feder1,2*,DmitriA.Petrov1,AlanO.Bergland1 1Department of Biology, Stanford University, Stanford, California, United States of America, 2Department of Mathematics, University of Pennsylvania, Philadelphia, Pennsylvania,UnitedStatesofAmerica Abstract High-throughputpooledresequencingofferssignificantpotentialforwholegenomepopulationsequencing.However,its main drawback is the loss of haplotype information. In order to regain some of this information, we present LDx, a computational tool for estimating linkag