Pancreatic intraductal papillary mucinous neoplasm with concomitant heterotopic pancreatic cystic neoplasia of the stomach a case report and review of the literature 英文参考文献.docVIP

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Pancreatic intraductal papillary mucinous neoplasm with concomitant heterotopic pancreatic cystic neoplasia of the stomach a case report and review of the literature 英文参考文献.doc

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Pancreatic intraductal papillary mucinous neoplasm with concomitant heterotopic pancreatic cystic neoplasia of the stomach a case report and review of the literature 英文参考文献

Tsapralisetal.DiagnosticPathology2010,5:4 /content/5/1/4 CASE REPORT OpenAccess Pancreaticintraductalpapillarymucinous neoplasmwithconcomitantheterotopic pancreaticcysticneoplasiaofthestomach:acase reportandreviewoftheliterature DimitriosTsapralis1,3,AlexandrosCharalabopoulos1,3,EvaKaramitopoulou2,3,DimitriosSchizas1,3, KonstantinosCharalabopoulos2,3*,TheodorosLiakakos1,3,AnastasiosMacheras1,3 Abstract A60-year-oldCaucasianmaleunderwentatotalpancreatectomyforamixedtypepancreaticintraductalpapillary mucinousneoplasm(IPMN)arisinginthemainandsecondarypancreaticducts.Duringsurgery,asubserosalpoly- poidmasswasnotedatthegreatercurvatureofthegastricantrumandwasenucleated.Thismasswasprovento beheterotopicpancreatictissuewithcysticneoplasiaoftheIPMNhistologicsubtype.Throughanextensivesearch oftheliterature,wefoundthatthisisthefirstcaseeverreportedwithsimultaneousexistenceofIPMNchanges,in themainandsecondaryductsoftheorthotopicpancreasandintheheterotopicpancreatictissueofthegastric wall. Introduction largecenters[10],theincidenceofthispathologicentity Recentliteraturesuggestseitheranincreasingincidence in heterotopic pancreatic tissue is extremely rare. It is ofcysticneoplasmsofthepancreas,orimproveddetec- not unusual to find pancreatic tissue in the stomach, tion and recognition of these lesions. Historically, duodenum,ileum,Meckel’sdiverticulumorattheumbi- autopsystudieshaverevealedasignificantprevalenceof licus.FeldmanandWeinberg[11]foundduodenalpan- cysticlesionsofthepancreas.Kimuraetal[1]foundcys- creatic tissue in 13,7% of 410 necropsy specimens. ticlesionsin24%of300consecutiveautopsyspecimens Pearson[12]estimatedthatheterotopicpancreatictissue amonganelderlyJapanesepopulation.Themostsignifi- couldbefoundinasmanyas2%ofautopsiesifitwere cant recent change in the diagnosis and treatment of soughtcarefully. Inspiteoftherelatively commonpre- pancreatic cystic neoplasms istherecognition ofintra- senceofheterotopicpancreas,mainlyasasile