Pre-hospital antibiotic treatment and mortality caused by invasive meningococcal disease, adjusting for indication bias 英文参考文献.docVIP

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Pre-hospital antibiotic treatment and mortality caused by invasive meningococcal disease, adjusting for indication bias 英文参考文献.doc

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Pre-hospital antibiotic treatment and mortality caused by invasive meningococcal disease, adjusting for indication bias 英文参考文献

BMC Public Health BioMedCentral Research article Open Access Pre-hospital antibiotic treatment and mortality caused by invasive meningococcal disease, adjusting for indication bias Emilio Perea-Milla1,6, Julián Olalla*1, Emilio Sánchez-Cantalejo2,6, Francisco Martos3, Petra Matute-Cruz4, Guadalupe Carmona-López2,6, Yolanda Fornieles2, Aurelio Cayuela5, Javier García-Alegría1,6 and the ANCA Group Address: 1Hospital Costa del Sol, Marbella, Spain, 2Escuela Andaluza de Salud Pública, Granada, Spain, 3Facultad de Medicina, Universidad de Málaga, Málaga, Spain, 4Dirección General de Salud Pública, Tenerife, Spain, 5Hospital Virgen del Rocío, Seville, Spain and 6CIBER Epidemiología y Salud Pública (CIBERESP), Barcelona, Spain Email: Emilio Perea-Milla - eperea@hcs.es; Julián Olalla* - julio.olalla@; Emilio Sánchez- Cantalejo - emilio.sanchezcantalejo.easp@juntadeandalucia.es; Francisco Martos - fmartos@uma.es; Petra Matute- Cruz - petra.matutecruz@; Guadalupe Carmona-López - guadalupe.carmona.easp@juntadeandalucia.es; Yolanda Fornieles - yolanda.fornieles.easp@juntadeandalucia.es; Aurelio Cayuela - aurelio.cayuela.sspa@juntadeandalucia.es; Javier García- Alegría - JGALEGRI@terra.es; the ANCA Group - eperea@hcs.es * Corresponding author Published: 3 April 2009 Received: 9 September 2008 Accepted: 3 April 2009 BMC Public Health 2009, 9:95 doi:10.1186/1471-2458-9-95 This article is available from: /1471-2458/9/95 ? 2009 Perea-Milla et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background: Mortality from invasive meningococcal disease (IMD) has remained stable over the last thirty years and it is unclear whether pre-hospital antibiotherapy actually produces a decrease in this mortality. Our aim was to examin