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Prevalence and risk factors of diabetes and impaired fasting glucose in Nauru 英文参考文献
Khambaliaetal.BMCPublicHealth2011,11:719
/1471-2458/11/719
RESEARCH ARTICLE
OpenAccess
Prevalenceandriskfactorsofdiabetesand
impairedfastingglucoseinNauru
AminaKhambalia1,PhilayrathPhongsavan2*,BenJSmith3,KierenKeke4,LiDan5,AndrewFitzhardinge6and
AdrianEBauman2
Abstract
Background:NocomprehensiveassessmentofdiabetesprevalenceinNauruhasbeenconductedsincean
extremeprevalencewasdocumentedmorethantwodecadesago.Thisstudyaimstodeterminetheprevalence
andriskfactorsofdiabetesandimpairedfastingglucose.
Methods:Anationwidesurveyin2004ofpeopleaged15-64years(n=1592).Fastingplasmaglucoselevelswere
usedtodefineddiabetes(≥7.0mmol/lor126mg/dl)andprediabetes(6.1-6.9mmol/lor110-125mg/dl).
Results:Thesex-standardizedprevalenceofdiabeteswas13.0%(95%CI:10.6,15.4)inmen,14.4%(11.9,16.9)in
women,and13.7%(12.0,15.4)combined.Thesex-standardizedprevalenceofprediabeteswas6.4%(4.6,8.2)for
men,5.5%(3.9,7.2)forwomen,and6.0%(4.8,7.3)combined.Theprevalenceofdiabetesforindividuals15-24,
25-34,35-44,45-54and55-64yearswas4.5%,7.6%,24.1%,32.9%,and42.7%,respectively.Theprevalenceof
prediabetesforthesameagecategorieswas4.2%,8.8%,5.9%,6.6%,7.1%,respectively.Multivariable,multinomial
logitmodelingfoundriskfactorsforprediabeteswerehighcholesterollevels(OR:2.02,95%CI:1.66,2.47)and
elevatedwaistcircumference(OR:1.04,95%CI:1.00,1.08),andfordiabeteswereageinyears(OR:1.06;95%CI:
1.04,1.07),cholesterollevels(OR:1.84,95%CI:1.58,2.14)andwaistcircumference(OR:1.04,95%CI:1.02,1.07).
Conclusions:DiabetesremainsamajorpublichealthprobleminNauru,affectingoneoutofeverytenpeople.
Whiletheprevalenceofdiabeteshasdeclined,itsburdenhaspersistedamongtheoldbutalsoextendedtowards
theyoungeragegroups.
Keywords:riskfactors,epidemiology,adultdiabetes,populationstudies
Background
incidence of diabetes in Pima Indians was 38.2 cases/
TheprevalenceofdiabetesinNauruhaspreviouslybeen 1,000person-yearsin1965,comparedto26.2cases/1,000
reportedtobeextremelyhigh.In1975,theprevalenceof person-yearsin1975/1976-1982amongNauruans[2
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