Recombinant activated factor VIIa for the treatment of bleeding in major abdominal surgery including vascular and urological surgery a review and meta-analysis of published data 英文参考文献.docVIP

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Recombinant activated factor VIIa for the treatment of bleeding in major abdominal surgery including vascular and urological surgery a review and meta-analysis of published data 英文参考文献.doc

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Recombinant activated factor VIIa for the treatment of bleeding in major abdominal surgery including vascular and urological surgery a review and meta-analysis of published data 英文参考文献

Available online /content/12/1/R14 Research Open Access Vol 12 No 1 Recombinant activated factor VIIa for the treatment of bleeding in major abdominal surgery including vascular and urological surgery: a review and meta-analysis of published data Christian von Heymann1, Sven Jonas2, Claudia Spies1, Klaus-Dieter Wernecke3, Sabine Ziemer4, Detlev Janssen5 and Jürgen Koscielny6 1Department of Anesthesiology and Intensive Care Medicine, Charité-University Medicine Berlin, Campus Virchow-Klinikum and Campus Charité Mitte, Augustenburger Platz 1, 13353 Berlin, Germany 2Department of General and Transplantation Surgery, Charité-University Medicine Berlin, Campus Virchow-Klinikum, Augustenburger Platz 1, 13353 Berlin, Germany 3Sophisticated Statistical Analysis (SOSTANA) GmbH, Berlin, Wildensteiner Str. 27, 10318 Berlin, Germany 4Institute of Laboratory Medicine and Pathological Biochemistry, Charité-University Medicine Berlin, Charitéplatz 1, 10117 Berlin, Germany 5Med-i-Scene Concept GmbH, Schlesierstr. 9, 91085 Weisendorf, Germany 6Institute of Transfusion Medicine, Charité-University Medicine Berlin, Charitéplatz 1, 10117 Berlin, Germany Corresponding author: Christian von Heymann, christian.von_heymann@charite.de Received: 30 Nov 2007 Revisions requested: 23 Jan 2008 Revisions received: 7 Feb 2008 Accepted: 15 Feb 2008 Published: 15 Feb 2008 Critical Care 2008, 12:R14 (doi:10.1186/cc6788) This article is online at: /content/12/1/R14 ? 2008 von Heymann et al.; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background The purpose of this study was to determine the role of recombinant activated factor VII (rFVIIa) in abdominal, vascular, and urological surgery. probability of survival of 53.0% (95% CI 26.4% to