Synthesis of New Anthihelmintic Analogs of Marine Natural Products 英文参考文献.docVIP

313 Molecules 2000, 5 Synthesis of New Anthihelmintic Analogs of Marine Natural Products* Gloria Serra, Graciela Mahler, Sandra Gordon, Marcelo Incerti and Eduardo Manta Cátedra de Química Farmacéutica. Facultad de Química, Universidad de la República.Av. General Flores 2124, C.C. 1157, Montevideo, Uruguay Abstract: The synthesis of new anthelmintic compounds derived from 2-amine-4-hydroxy- δ-valerolactams and 2,4-dialkylthiazoles is described. The synthetic procedures and biologi- cal activity data for these compounds will be presented. Secondary metabolites of marine origin are a sou