Synthetic α-Conotoxin Mutants as Probes for Studying Nicotinic Acetylcholine Receptors and in the Development of Novel Drug Leads 英文参考文献.docVIP

Toxins 2010, 2, 1471-1499; doi:10.3390/toxins2061471 OPEN ACCESS toxins ISSN 2072-6651 /journal/toxins Review Synthetic ?-Conotoxin Mutants as Probes for Studying Nicotinic Acetylcholine Receptors and in the Development of Novel Drug Leads Christopher J. Armishaw Torrey Pines Institute for Molecular Studies, 11350 SW Village Pkwy, Port St Lucie, FL 34987, USA; E-Mail: carmishaw@; Tel.: +1-772-345-4720; Fax: +1-772-345-3649 Received: 1 April 2010; in revised form: 27 May 2010 / Accepted: 11 June 2010/ Published: 14 June 2010 Abstract: α-Conotoxins are peptide neurotoxins isolated from v