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Protein family review
The claudins
Madhu Lal-Nag* and Patrice J Morin*?
Addresses: *Laboratory of Cellular and Molecular Biology, National Institute on Aging, Baltimore, National Institutes of Health Biomedical
Research Center, MD 21224, USA. ?Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA.
Correspondence: Patrice J Morin. Email: morinp@
development [2]. Consistent with this hypothesis is the
presence of highly homologous CLDN genes located in
close proximity in various mammalian genomes (see
below). Interestingly,
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