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The effect of halothane and pentobarbital sodium on brain ependymal cilia 英文参考文献
O’CallaghanandSikandCilia2012,1:12
/content/1/1/12
RESEARCH
OpenAccess
Theeffectofhalothaneandpentobarbitalsodium
onbrainependymalcilia
ChrisO’Callaghan2*andKulvinderSikand1
Abstract
Background:Theeffectofanestheticagentsonependymalciliaryfunctionisunknown.Theaimofthisstudywas
todeterminetheeffectofhalothaneandpentobarbitalsodiumonbrainependymalciliaryfunction.
Methods:Weusedanexvivoratbrainslicemodeltomeasureependymalciliarybeatfrequencybyhighspeed
videophotographyat37°C.
Results:Exposuretohalothanecausedasignificantreductioninciliarybeatfrequencyof2%(P=0.006),15.5%
(P0.001),and21.5%(P0.001
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