The fine specificity of IgM anti-citrullinated protein antibodies (ACPA) is different from that of IgG ACPA 英文参考文献.docVIP

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The fine specificity of IgM anti-citrullinated protein antibodies (ACPA) is different from that of IgG ACPA 英文参考文献.doc

The fine specificity of IgM anti-citrullinated protein antibodies (ACPA) is different from that of IgG ACPA 英文参考文献

Suwannalaietal.ArthritisResearchTherapy2011,13:R195 /content/13/6/R195 RESEARCH ARTICLE OpenAccess ThefinespecificityofIgManti-citrullinated proteinantibodies(ACPA)isdifferentfromthat ofIgGACPA ParaweeSuwannalai1,AnnemiekWillemze1,LindavanToorn1,GerrieStoeken-Rijsbergen1,NivineLevarht1, JanWouterDrijfhout2,TomWJHuizinga1,ReneEMToes1andLeendertATrouw1* Abstract Introduction:TheantigenrecognitionpatternofimmunoglobulinM(IgM)could,whendirectedagainstprotein antigens,provideanindicationoftheantigenicmoietiestriggeringnewBcells.Thehalf-lifeofIgMisshortand memoryBcellsagainstT-cell-dependentprote

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The fine specificity of IgM anti-citrullinated protein antibodies (ACPA) is different from that of IgG ACPA 英文参考文献.docVIP