The generation of chromosomal deletions to provide extensive coverage and subdivision of the Drosophila melanogaster genome 英文参考文献.docVIP
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The generation of chromosomal deletions to provide extensive coverage and subdivision of the Drosophila melanogaster genome 英文参考文献
Cooketal.GenomeBiology2012,13:R21
/2012/13/3/R21
RESEARCH
OpenAccess
Thegenerationofchromosomaldeletionsto
provideextensivecoverageandsubdivisionof
theDrosophilamelanogastergenome
RKimberleyCook,StaceyJChristensen,JenniferADeal,RachelACoburn,MeganEDeal,JillMGresens,
ThomasCKaufmanandKevinRCook*
Abstract
Background:ChromosomaldeletionsareusedextensivelyinDrosophilamelanogastergeneticsresearch.Deletion
mappingistheprimarymethodusedforfine-scalegenelocalization.Effectiveandefficientdeletionmapping
requiresbothextensivegenomiccoverageandahighdensityofmolecularlydefinedbreakpointsacrossthe
genome
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