The genetics of generalized vitiligo autoimmune pathways and an inverse relationship with malignant melanoma 英文参考文献.docVIP

Spritz Genome Medicine 2010,2:78 /content/2/10/78 MINIRE VIE W The genetics of generalized vitiligo: autoimmune pathways and an inverse relationship with malignant melanoma Richard A Spritz* epidemiological evidence indicates that GV is a complex Abstract trait involving multiple genes and unknown environ- Generalized vitiligo (GV) is the most common pigmentation disease, in which white spots of skin and overlying hair result from loss of melanocytes from the involved regions. GV is a complex disease involving both genetic predisposition and unknown environmental triggers. Wher