The exome factor 英文参考文献.docVIP

Stower Genome Biology 2011,12:407 /2011/12/9/407 EDITORIAL The exome factor Hannah Stower prioritization of variants from exome sequencing data. With typically 15,000 to 20,000 variants discovered per exome, whittling these variants down to those that are likely to be causing disease is a signi?cant challenge. An abundance of tools has been developed for this task, and the Review therefore sets out to consider the relative Abstract Exome sequencing is rapidly expanding both as a technique and in its biological applications. e decision to launch a special is