The interaction of genetic variants and DNA methylation of the interleukin-4 receptor gene increase the risk of asthma at age 18 years 英文参考文献.docVIP

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The interaction of genetic variants and DNA methylation of the interleukin-4 receptor gene increase the risk of asthma at age 18 years 英文参考文献.doc

The interaction of genetic variants and DNA methylation of the interleukin-4 receptor gene increase the risk of asthma at age 18 years 英文参考文献

Soto-Ramírezetal.ClinicalEpigenetics2013,5:1 /content/5/1/1 RESEARCH OpenAccess TheinteractionofgeneticvariantsandDNA methylationoftheinterleukin-4receptorgene increasetheriskofasthmaatage18years NelísSoto-Ramírez1,SyedHasanArshad2,6,JohnWHolloway2,3,HongmeiZhang1,EricSchauberger4,SusanEwart5, VeereshPatil2,6andWilfriedKarmaus1* Abstract Background:Theoccurrenceofasthmaisweaklyexplainedbyknowngeneticvariants.Epigeneticmarks,DNA methylation(DNA-M)inparticular,areconsideredtoaddtotheexplanationofasthma.However,noetiological modelhasyetbeendevelopedthatintegratesgeneticvariantsandDNA-M.Toexplor

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