A Novel Class of Selective Acetylcholinesterase Inhibitors Synthesis and Evaluation of (E)-2-(Benzo[d]thiazol-2-yl)-3-heteroarylacrylonitriles.docVIP

Molecules 2012, 17, 12072-12085; doi:10.3390/molecules171012072 OPEN ACCESS molecules ISSN 1420-3049 /journal/molecules Article A Novel Class of Selective Acetylcholinesterase Inhibitors: Synthesis and Evaluation of (E)-2-(Benzo[d]thiazol-2-yl)-3- heteroarylacrylonitriles Pedro de la Torre 1,2, Luis Astudillo Saavedra 1, Julio Caballero 2, Jairo Quiroga 3, Jans H. Alzate-Morales 2, Margarita Gutiérrez Cabrera 1,* and Jorge Trilleras 4,* 1 Laboratorio Síntesis Orgánica, Instituto de Química de Recursos Naturales, Universidad de Talca, Casilla 747, Talca, 3460000, Chile 2 Centro de Bioinfo