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A novel mode of chromosomal evolution peculiar to filamentous Ascomycete fungi
Haneetal.GenomeBiology2011,12:R45
/2011/12/5/R45
RESEARCH
OpenAccess
Anovelmodeofchromosomalevolutionpeculiar
tofilamentousAscomycetefungi
JamesKHane1,2,ThierryRouxel3,BarbaraJHowlett4,GertHJKema5,StephenBGoodwin6andRichardPOliver7*
Abstract
Background:Geneloss,inversions,translocations,andotherchromosomalrearrangementsvaryamongspecies,
resultingindifferentratesofstructuralgenomeevolution.Majorchromosomalrearrangementsarerareinmost
eukaryotes,givinglargeregionswiththesamegenesinthesameorderandorientationacrossspecies.These
regionsofmacrosyntenyhavebeenveryusefulforlocatinghomologousgenesindi
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