A paragon of self-tolerance CD25+CD4+ regulatory T cells and the control of immune responses.docVIP

Available online /content/6/1/19 Review A paragon of self-tolerance: CD25+CD4+ regulatory T cells and the control of immune responses Zoltán Fehérvári and Shimon Sakaguchi Department of Experimental Pathology, Kyoto University, Kyoto, Japan Correspondence: Shimon Sakaguchi (e-mail: shimon@frontier.kyoto-u.ac.jp) Received: 23 Sep 2003 Accepted: 3 Dec 2003 Published: 19 Dec 2003 Arthritis Res Ther 2004, 6:19-25 (DOI 10.1186/ar1037) ? 2004 BioMed Central Ltd (Print ISSN 1478-6354; Online ISSN 1478-6362) Abstract The interest in naturally arising regulatory T (T ) cells as a paradigm for ma