原创力文档A randomized trial of 7-day doripenem versus 10-day imipenem-cilastatin for ventilator-associated pneumonia.docVIP
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A randomized trial of 7-day doripenem versus 10-day imipenem-cilastatin for ventilator-associated pneumonia
Kollefetal.CriticalCare2012,16:R218
/content/16/6/R218
RESEARCH
OpenAccess
Arandomizedtrialof7-daydoripenemversus
10-dayimipenem-cilastatinforventilator-
associatedpneumonia
MarinHKollef1*,JeanChastre2,MarcClavel3,MarcosIRestrepo4,BartMichiels5,KonéKaniga6,IolandaCirillo6,
HollyKimko6andRebeccaRedman6
Abstract
Introduction:Theaimofthisstudywastocomparea7-daycourseofdoripenemtoa10-daycourseof
imipenem-cilastatinforventilator-associatedpneumonia(VAP)duetoGram-negativebacteria.
Methods:Thiswasaprospective,double-blinded,randomizedtrialcomparingafixed7-daycourseofdoripenem
onegramasafour-hourinf
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