A robust approach based on Weibull distribution for clustering gene expression data.docVIP

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A robust approach based on Weibull distribution for clustering gene expression data.doc

A robust approach based on Weibull distribution for clustering gene expression data

Wangetal.AlgorithmsforMolecularBiology2011,6:14 /content/6/1/14 RESEARCH OpenAccess ArobustapproachbasedonWeibulldistribution forclusteringgeneexpressiondata HuakunWang1,2?,ZhenzhenWang1?,XiaLi1*,BinshengGong1,LixinFeng2andYingZhou2 Abstract Background:Clusteringisawidelyusedtechniqueforanalysisofgeneexpressiondata.Mostclusteringmethods groupgenesbasedonthedistances,whilefewmethodsgroupgenesaccordingtothesimilaritiesofthe distributionsofthegeneexpressionlevels.Furthermore,asthebiologicalannotationresourcesaccumulated,an increasingnumberofgeneshavebeenannotatedintofunctionalcategories.Asaresu

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